2 Results for "

 Aconitum carmichaeli Debx.

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for " Aconitum carmichaeli Debx." in MCE Product Catalog:

Talatisamine
Talatisamine
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Cat. No.: HY-N0663
CAS No.: 20501-56-8
Category:  

Alkaloids Pyrrole Alkaloids Ranunculaceae  Aconitum carmichaeli Debx. Plants

Target:  

Mitochondrial Metabolism Cyclophilin Potassium Channel

Talatisamine is an orally active cyclophilin D activator isolated from the roots of Aconitum carmichaeli Debx. Talatisamine exerts biological functions by activating cyclophilin D, inhibiting Ca 2+-dependent opening of the mitochondrial permeability transition pore (mPTP) (IC50=78 μM), and blocking delayed rectifier K + channels (IC50=146 μM). Talatisamine possesses both antioxidant and membrane-stabilizing properties, effectively inhibits lipid peroxidation and protects mitochondrial membrane function. Talatisamine exhibits multiple activities including antiarrhythmic, hypotensive, anti-inflammatory, anticancer and neuroprotective effects. Talatisamine finds applications in the research of ischemic diseases, rheumatoid arthritis, inflammation-related diseases and Alzheimer's disease .
Karacolidine
Karacolidine
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Cat. No.: HY-N17886
CAS No.: 41655-13-4
Category:  

Alkaloids Other Alkaloids Ranunculaceae  Aconitum carmichaeli Debx. Plants

Target:  

Drug Derivative

Karacolidine (compound 9) is an aconitine-type alkaloid. Karacolidine can be found in the lateral root of Aconitum carmichaeli Debx. (Radix Aconiti Lateralis) .
Assay Types